COMMENTARY ON INHALED 239PUO2 IN DOGS — A PROPHYLAXIS AGAINST LUNG CANCER?
35th Annual CNS Conference - 2015 May 31 - June 3


Presented at:
35th Annual CNS Conference
2015 May 31 - June 3
Location:
Saint John, Canada
Session Title:
3B2 - Medical Physics and Radiation Biology

Authors:
J. M. Cuttler (Cuttler and Associates)
L. E. Feinendegen (Brookhaven National Laboratory)
  

Abstract

Several studies on the effect of inhaled plutonium-dioxide particulates and the incidence of lung tumors in dogs reveal beneficial effects when the cumulative alpha-radiation dose is low. There is a threshold at an exposure level of about 100 cGy for excess tumor incidence and reduced lifespan. The observations conform to the expectations of the radiation hormesis dose-response model and contradict the predictions of the Linear No-Threshold (LNT) hypothesis. These studies suggest investigating the possibility of employing low-dose alpha-radiation, such as from 239PuO2 inhalation, as a prophylaxis against lung cancer.

 



Individual Conference-Paper Copies (Electronic Where Available):

  • For CNS members, the first 5 copies per calendar year are free, and additional copies are $10 each.
  • For non-members, the price is $25 for the first Conference-paper copy in a request, and $10 each for additional copies of papers in the same conference and in the same request.
  • Contact the CNS office to order reprints.